National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960078

Testing Status of Clarithromycin - M960078

 

CASRN: 81103-11-9

Formula: C38-H69-N-O13

Synonyms/Common Names

  • A-56268
  • Biaxin
  • Clathromycin
  • 6-O-Methylerythromycin
  • TE-031

Known Uses

Antibiotic derived from erythromycin that is active against a variety of microorganisms; antibacterial.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Genetic Toxicology

  • Salmonella  (A14443)  Completed 
    •  Negative 

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage)  (IMM97007)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 125, 250, OR 500 MG/KG.
  • 4 days Immunotoxicity (Topical Application)  (IMM97009)  Completed 
    • Female Mice: BALB/c
    • Dose: 0, .1%, .25%, .5%, 1%, 2%, OR 4%.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.