National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m960083

Testing Status of Halogenated ethanes CS (Pentabromoethane) - M960083

 

CASRN: 75-95-6

Formula: C2-H-Br5

Synonyms/Common Names

  • Pentabromoethane
  • Pentabromoethane (Halogenated ethanes CS)

Known Uses

In an attempt to determine some of the structure activity relationships involved in the induction of hyaline droplet nephropathy by halogenated ethanes, a series of commercially available ethanes substituted with three or more chlorines, four or more bromines, or a combination of chlorines and fluorines was studied in a short-term renal toxicity assessment in male F344/N rats.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 3 weeks (Gavage)  (C91020)  Report Complete 
    • TOX-45 (NIH Number: 96-3935)  (Tox Peer Review 08/00/1995A )
      Renal Toxicity Studies of Selected Halogenated Ethanes Administered by Gavage to F344/N Rats
    • Rats: F344/N
    • Dose: MALE RATS 0, 0.62, 1.24 MMOL/KG/DAY; 5/GRP.
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