Testing Status of Halogenated ethanes CS (Pentabromoethane) M960083
- Pentabromoethane (Halogenated ethanes CS)
In an attempt to determine some of the structure activity relationships involved in the induction of hyaline droplet nephropathy by halogenated ethanes, a series of commercially available ethanes substituted with three or more chlorines, four or more bromines, or a combination of chlorines and fluorines was studied in a short-term renal toxicity assessment in male F344/N rats.
- 3 weeks (Gavage)
- Rats: F344/N
- Dose: MALE RATS 0, 0.62, 1.24 MMOL/KG/DAY; 5/GRP.