National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m970007

Testing Status of Transgenic LEP (Melphalan) - M970007

 

CASRN: 148-82-3

Related: MELPHALAN

Formula: C13-H18-Cl2-N2-O2

Synonyms/Common Names

  • Melphalan (Transgenic LEP)

Known Uses

Chemotherapeutic used to treat multiple myeloma, cancer of the ovary.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 26 weeks (Gavage)  (C97001D)  Completed 
    • Mice: CB6F1; Mice: Tg/RASH2/CB6F1
    • Dose: 0, 0.3, OR 1.5 MG/KG; 15/GROUP TREATED -- 10/GROUP CONTROLS.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.