National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m970021

Testing Status of Retinoid project 6 (4-HPR) - M970021

 

CASRN: 65646-68-6

Related: SEE RETINOID PROJECTS 1,2,3,4,5

Formula: C26-H33-N-O2

Synonyms/Common Names

  • 4-HPR (Retinoid project 6)
  • 4-Hydroxyphenyl (Retinoid project 6)

Known Uses

Project combining various forms of vitamin A (retinoids) to examine their use in the prevention & intervention of breast cancer.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 18 & 26 weeks (Dosed-Feed)  (C93028J)  Completed 
    • Mice: MMTV/NEU (Tg.Nk)
    • Dose: MICE ONLY: AIN 76-A & NTP 2000 FEED CONTROLS. 4-HPR ADMINISTERED AT 2741 MG/KG.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.