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Testing Status of alpha/beta Hydroxy acids (glycolic acid, salicylic acid) M970035



Synonyms/Common Names

  • Glycolic acid (alpha/beta Hydroxy acids)
  • Salicylic acid (alpha/beta Hydroxy acids)


  • 79-14-1 - Glycolic acid
  • 69-72-7 - Salicylic acid

Known Uses

Chemical peels of the skin. As part of the alpha/beta-hydroxy acids initiative. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Long-Term Carcinogenicity

  • 1 year (Topical Application)  (C97010A)  Report Review 
    • TR-524 (NIH Number: 07-4472)  (Peer Review Approval 09/27/2005A )
      Photocarcinogenesis Study of Glycolic Acid and Salicylic Acid (CASRNs 79-14-1 and 69-72-7) in SKH-1 Mice (Simulated Solar Light and Topical Application Studies)
    • Mice: SKH-1 Hairless
    • Carcinogenesis Results
      • Male Mice No Evidence 
      • Female Mice No Evidence