Testing Status of Water disinfection byproducts (Dibromoacetonitrile) M970038

 

CASRN: 3252-43-5

Formula: C2-H-Br2-N

Synonyms/Common Names

  • Dibromoacetonitrile (Water disinfection byproducts)

Known Uses

Formed as a result of the reaction of chlorine oxidizing compounds (e.g., chlorine gas, hypochlorous acid, and hypochlorite) with natural organic matter, particularly nitrogen-containing organic compounds, in water containing bromine; it is also a by-product of ozone disinfection.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Dosed-Water)  (C96015)  Completed 
    • Rats: F344/N; Mice: B6C3F1/N
    • Dose: R&M: 0, 12.5, 25, 50, 100, OR 200 MG/L; 5/SEX/SPECIES.
  • 13 weeks (Dosed-Water)  (C96015)  Completed 
    • Rats: F344/N; Mice: B6C3F1/N
    • Dose: R&M: 0, 12.5, 25, 50, 100, OR 200 MG/L; 20 SEX/SPECIES.

Long-Term Carcinogenicity

  • 2 years (Dosed-Water)  (C96015)  Completed 
    • TR-544 (NIH Number: 10-5886)  (Peer Review Approval 02/27/2008A )
      Toxicology and Carcinogenesis Studies of Dibromoacetonitrile (CASRN 3252-43-5) in F344/N Rats and B6C3F1 Mice (Drinking Water studies)
    • Rats: F344/N; Mice: B6C3F1/N
    • Carcinogenesis Results
      • Male Rats Clear Evidence 
      • Female Rats Some Evidence 
      • Male Mice Clear Evidence 
      • Female Mice Clear Evidence 
    • Dose: R&M: 0, 50 100, OR 200 MG/L; 50 SEX/SPECIES/DOSE.