Testing Status of Itraconazole M970064

 

CASRN: 84625-61-6

Formula: C35-H38-Cl2-N8-O4

Synonyms/Common Names

  • 4-(4-(4-(4-((2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
  • Itraconazole (AIDS Initiative)
  • Sporonox

Known Uses

Antifungal. Treatment for fungal infections and is being studied for prevention of histoplasmosis, and for treatment of mild cases of histoplasmosis and blastomycosis.

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage)  (IMM97008)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 10, 20, 40, 80, OR 160 MG/KG/DAY.