National Toxicology Program

National Toxicology Program

Testing Status of Azithromycin (AIDS Initiative) - M970075


CASRN: 83905-01-5

Formula: C38-H72-N2-O12

Synonyms/Common Names

  • N-methyl-11-aza-10-deoxo-10-dihydroerythromycin A
  • 1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
  • Sumamed
  • Zithromax

Known Uses

Antibiotic used in combination with other drugs as preventive treatment against both toxoplasmosis and mac. Also used for treating cryptosporidoiosis.

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • 4 days Immunotoxicity (Topical Application)  (IMM97010)  Completed 
    • Mice: BALB/c
    • Dose: 10, 20, OR 40% (W/V).
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.