National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m970085

Testing Status of Agent orange mixture - M970085

 

CASRN: AGNTORANGEMX

Related: 2,4-D; 2,4,5-T, TCDD

Formula: N/A

Synonyms/Common Names

  • Simulated Agent Orange

Secondary:

  • 94-75-7 - 2,4-Dichlorophenoxyacetic acid
  • 94-75-7 - Peroxisome project (2,4-Dichlorophenoxyacetic acid)
  • 1746-01-6 - Toxic equivalency factor evaluation (TCDD)
  • 1746-01-6 - TEF transgenics (TCDD)
  • 1746-01-6 - 2,3,7,8-Tetrachlorodibenzo-p-dioxin
  • 1746-01-6 - Transgenic Model Evaluation (2,3,7,8-Tetrachlorodibenzodioxin)
  • 93-76-5 - 2,4,5-Trichlorophenoxyacetic acid

Known Uses

Special study of the mixture of 2,4-D, 2,4,5-T & TCDD (simulated agent orange). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Organ Systems Toxicity

  • Other Reproductive Studies (Dosed-Feed)  (ORST80001)  Completed 
    • Citation: Evaluation of 2,4-Dichlorophenoxyacetic Acid (2,4-D), 2,4,5-Trichlorophenoxyacetic Acid (2,4,5-T) and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Toxicity in C57BL/6 Mice: Reproduction and Fertility in Treated Male Mice and Evaluation of Congenital Malformations in their Offspring.
    • Male Mice: C57BL/6
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