Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Goldenseal extract M980047

 

CASRN: 84603-60-1

Formula: N/A

Synonyms/Common Names

  • EGS
  • Extract of goldenseal
  • Goldenseal, Hydrastis canadensis extract
  • Hydrastis canadensis extract

Known Uses

Natural herbal remedy from root extract, used by native Americans to treat wounds, ulcers, digestive disorders, and skin and eye ailments. Also used to treat a variety of digestive and hemorrhagic disorders. Thought to possess slight antiseptic, astringent, and hemostatic qualities when applied topically. Commonly consumed as an herbal tea. (NTP exec. Summary - 1997)

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 5 days (Gavage)  (C98047)  Data in Review 
    • 5 day
    • Rats: F344/NCrl (SAS FISCH)
    • Dose: Golden Seal Extract; 0, 94, 188, 375, 750, or 1500 mg/kg; 6 males/group.

Genetic Toxicology

  • Micronucleus (Gavage)  (G98047)  On Test 
    • Rats: F344/N Charles River

Toxicogenomics

  • Microarray Analysis (Gavage)  (T98047)  Data in Review 
    • Rats: F344/NTac