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Testing Status of Camptothecin M980052


CASRN: 7689-03-4

Formula: C20-H16-N2-O4

Synonyms/Common Names

  • 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-

Known Uses

Antineoplastic agent; phytogenic. Alkaloid exhibiting antileukemic and antitumor activities isolated from the stem wood of the Chinese tree camtotheca acuminata (Merck, 11th ed)

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • single exposure Total Reproductive Capacity (Intraperitoneal Injection)  (TRC98033)  Completed 
    • Female Mice: (SEC/E X C57BL/E)F1
    • Dose: 10 MG/KG.