National Toxicology Program

National Toxicology Program

Testing Status of Annatto - M980055


CASRN: 1393-63-1


Synonyms/Common Names

  • Annatta Extract
  • Annotta
  • Arnatta
  • CI 75120
  • Ci Natural Orange 4

Known Uses

Color additive in food, body care products. Used in wood stains and varnishes and in dyeing silk.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Planned Carcinogenicity/Toxicity

  • Selected (C99015)  

    Genetic Toxicology

    • Salmonella  (A44526)  Completed 
      •  Positive 
    • Salmonella  (A50684)  Completed 
      •  Positive 
    • Salmonella  (A82879)  Completed 
      •  Positive 

    Organ Systems Toxicity

    • 3 to 7 days Hypersensitivity (Topical Application)  (IMM20405)  Completed 
      • Female Mice: BALB/c
      • Dose: 0, 5 OR 10%.
    NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.