Testing Status of Water disinfection byproducts (Bromochloroacetic acid) M980085

 

CASRN: 5589-96-8

Formula: C2-H2-Br-Cl-O2

Synonyms/Common Names

  • Bromochloroacetic acid
  • Bromochloroacetic acid (Water disinfection byproducts)

Known Uses

EPA water chemical; byproduct of water chlorination

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Dosed-Water)  (C96019)  Completed 
    • Rats: F344/N; Mice: B6C3F1/N
    • Dose: R&M: 0, 62.5, 125, 250, 500, OR 1000 MG/L; 10 SEX/SPECIES.
  • 13 weeks (Dosed-Water)  (C96019)  Completed 
    • Rats: F344/N; Mice: B6C3F1/N
    • Dose: R&M: 0, 62.5, 125, 250, 500, OR 1000 MG/L; 20/SEX/SPECIES.

Long-Term Carcinogenicity

  • 2 years (Dosed-Water)  (C96019)  Completed 
    • TR-549 (NIH Number: 09-5890)  (Peer Review Approval 02/27/2008A )
      Toxicology and Carcinogenesis Studies of Bromochloroacetic acid (CASRN 5589-96-8) in F344/N Rats and B6C3F1 Mice (Drinking water studies)
    • Rats: F344/N; Mice: B6C3F1/N
    • Carcinogenesis Results
      • Male Rats Clear Evidence 
      • Female Rats Clear Evidence 
      • Male Mice Clear Evidence 
      • Female Mice Clear Evidence 
    • Dose: R&M: 0, 250, 500, OR 1000 MG/L; 50/SEX/SPECIES/DOSE.