National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m990030

Testing Status of Prevention 2 (Silymarin) - M990030

 

CASRN: 65666-07-1

Synonyms/Common Names

  • Legalon
  • SILYMARIN (PREVENTION 2)

Known Uses

Drug/therapeutic agent. Prevention 2 is a special study to examine dietary intervention to prevent/delay breast cancer.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Short-Term Toxicity

  • 26 weeks (Dosed-Feed)  (C99014B)  Completed 
    • Mice: MMTV/NEU (Tg.Nk)
    • Dose: 0, 0.05, 0.10, OR 0.20%.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.