National Toxicology Program

Testing Status of Aloe vera gel - M990056

CASRN: 8001-97-6

Synonyms/Common Names

• Aloe vera

Known Uses

Aloe gel is used in health-oriented drinks, cosmetics and personal care products. Used to promote rapid healing of burns, dermal ulcers & wounds and to impede bacterial growth on the skin.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Long-Term Carcinogenicity

• 40 weeks (Topical Application)  (C20116C)  Report Complete 
  • TR-553 (NIH Number: 10-5894)  (Peer Review Approval 02/27/2008A )
    Photococarcinogenesis Study of Aloe Vera [CASRN 481-72-1 (Aloe-emodin)] in SKH-1 Mice (Simulated Solar Light and Topical Application Study)
  • Mice: SKH-1 Hairless
  • Dose: 0, 3%, or 6% compound with simulated light exposures.

Genetic Toxicology

• Salmonella  (A20251)  Completed 
  •  Negative 
• Salmonella  (G99056)  Completed 
  •  Negative