National Toxicology Program

National Toxicology Program

Testing Status of Silybin - M990088


CASRN: 22888-70-6

Formula: C25-H22-O10

Synonyms/Common Names

  • 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl)-3,5,7-trihydroxy-, (2R-(2-alpha,3-beta,6(2R*,3R*)))-(9CI)

Known Uses

A principal component of silymarin found in milk thistle fruit; dietary supplement

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Genetic Toxicology

  • Salmonella  (A42362)  Completed 
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.