National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/msr-5

Management Status Report: Reference 5

Short-Term Exposure Studies in Progress
CHEMICAL NAME
SYNONYM(S)
PRIMARY
CASRN
USE ROUTE SPECIES REPEAT
DOSE
START
DATE
SUBCHRONIC
START
DATE
Acrylamide
2-Propenamide
79-06-1 COMT/SYN GAV HSD 04/17A
Aflatoxin B1 (TGMX)
Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-me thoxy-, (6aR-cis)-
TGMX Aflatoxin B1
1162-65-8 LABC/NATL INHAL R2
Aloin
1,8-Dihydroxy-3-hydroxymethyl-10-(6-hydroxymethyl-3,4,5-trihydroxy-2-pyranyl)anthrone
10-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
1415-73-2 NATL WATER RC 07/15A
Phenolic Benzotriazoles (2-(2H-Benzotriazol-2-yl)-4-tert-butylphenol)
PBZT
tBu-BZT
3147-76-0 ADHS GAV HSD 02/16A
Bisphenol AF
2,2-Bis(4-hydroxyphenyl)perfluoropropane
BP-AF
BPAF
Phenol, 4,4'-(2,2,2-trifluoro-1-(trifluoromethyl)ethylidene)bis-
1478-61-1 GAV HSD 04/17A
Bisphenol S
Bis(4-hydroxyphenyl)sulfone
4,4'-Bisphenol S
4,4'-Dihydroxydiphenyl sulfone
DIPHONE
Phenol, 4,4'-sulfonylbis-
1,1'-Sulfonylbis(4-hydroxybenzene)
80-09-1 ADHS FEED M3 03/17A
1,2-Bis(2,4,6-tribromophenoxy)ethane
Benzene, 1,1'-(1,2-ethanediylbis(oxy))bis(2,4,6-tribromo- (9CI)
1,2-Bis(2,4,6-tribromophenoxy)ethane
BTBPE
Firemaster 680
Flame Retardant 2
37853-59-1 FLAM GAV HSDE 11/16A
N-Butylbenzenesulfonamide
Benzenesulfonic acid butyl amide
NBBS
3622-84-2 PLAS/SYN FEED M22 02/14A
Coumarin
2H-1-Benzopyran-2-one
91-64-5 PHAR/NATL GAV HSD 04/17A
Crude MCHM
CRUDEMCHM IND/SYN GAV HSD 09/14A
Crumbrubber various
CRUMBRUBBERVARIOUS N/S/SYN M22 02/17A
Decabromodiphenyl Ether
BDE-209
Deca BDE
2,2',3,3',4,4',5,5',6,6'-decabromodiphenyl ether (BDE-209)
Flame Retardant 2
1,1'-Oxybis(2,3,4,5,6-pentabromobenzene)
1163-19-5 FLAM GAV HSDE 11/16A
Di(2-ethylhexyl) Phthalate
1,2-Benzenedicarboxylic acid, bis(2-ethylhexyl) ester
Bis(2-ethylhexyl) phthalate
DEHP
Diethylhexyl phthalate
117-81-7 PLAS/SYN GAV HSD 03/17A
Dimethylamine Borane
Borane, compd. with dimethylamine (1:1)
Boron, trihydro(N-methylmethanamine)-, (beta-4)-
DMAB
74-94-2 DERMAL HSD M22 01/14A
2,2'-Dimorpholinodiethyl Ether
2,2'-Dimorpholinyldiethyl ether
DMDEE
Morpholine
Morpholine, 4,4'-(oxydi-2,1-ethanediyl)bis-
6425-39-4 IND/SYN GAV M22 04/16A
Phenolic Benzotriazoles (Drometrizole)
Drometrizol
PBZT
2440-22-4 IND GAV HSD 02/16A
1,2-bis(pentabromophenyl)ethane
DBDPE
Flame Retardant 2
84852-53-9 FLAM/SYN GAV HSDE 11/16A
Ethinyl estradiol
19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-
57-63-6 PHAR/N/S GAV HSD 04/17A
2-ethyltoluene
C9 Alkylbenzenes
611-14-3 LABC INHAL M22 HSD 11/15A
3-ethyltoluene
C9 Alkylbenzenes
620-14-4 LABC INHAL M22 HSD 10/15A
4-ethyltoluene
C9 Alkylbenzenes
622-96-8 FUEL INHAL R8 M22 08/15A
Fenofibrate
Tricor
49562-28-9 PHAR/SYN GAV HSD 03/17A
Garcinia Cambogia Extract
Brindal berry
Gamboge
GCE
90045-23-1 DIET/NATL FEED M22 HSD 04/14A
Ginkgo biloba extract
GBE
Maidenhair extract
90045-36-6 DIET/NATL GAV FSAS 12/15A
Ginseng
Panax
Prosapogenin
50647-08-0 DIET/NATL GAV HSD 03/17A
Goldenseal extract
EGS
Extract of goldenseal
Goldenseal, Hydrastis canadensis extract
Hydrastis canadensis extract
84603-60-1 NATL/N/S GAV FSAS 12/15A
Green Tea Extract
GTE
GREENTEAEXTR DIET/NATL GAV FSAS 01/16A
1,3,5,7,9,11-Hexabromocyclododecane
Cyclododecane, hexabromo-
Flame Retardant 2
1,3,5,7,9,11-HBCD
25637-99-4 FLAM GAV HSDE 11/16A
Hexachlorobenzene
Amatin
118-74-1 FUNG/SYN GAV HSD 04/17A
Hexachlorocyclopentadienyl-dibromocyclooctane
Flame Retardant 2
HCDBCO
51936-55-1 FLAM/SYN GAV HSDE 11/16A
Phenolic Benzotriazoles (3-(2H-Benzotriazol-2-yl)-5-(1,1-dimethylethyl)-4-hydroxybenzenepropanoic acid, octyl ester)
PBZT
84268-23-5 ADHS GAV HSD 01/16A
Ionic Liquid: 1-Butyl-1-methylpyrrolidinium Chloride
BMPC
[BmPy]Cl
1-Butyl-1-methylpyrrolidinium chloride (ionic liquid)
479500-35-1 LABC/SYN WATER M22 HSD 08/13A
Ionic Liquid: N-Butylpyridinium Chloride
NBPC
[NBuPy]Cl
N-Butylpyridinium chloride (ionic liquid)
1124-64-7 ELEC/SYN WATER HSD M22 09/13A
Ionic Liquid: 1-Ethyl-3-methylimidazolium Chloride
Basionic (TM) ST 80
1-Ethyl-3-methylimidazolium Chloride (Ionic Liquid)
65039-09-0 IND/SYN WATER M22 HSD 05/13A
Isopropylated Phenol Phosphate
Durad 100
Flame Retardant 1
IPP
Isopropylated phenol phosphate (3:1)
Isopropylphenyl phosphate
Phenol isopropylated phosphate
68937-41-7 FLAM/SYN FEED M22 12/14A
Melamine + Cyanuric Acid combination
MELCYANCOMB ADHS/SYN GAV RC 07/11A
Melamine + Cyanuric Acid combination
MELCYANCOMB ADHS/SYN GAV RC 10/15A
4-Methylcyclohexanemethanol
Cyclohexanemethanol, 4-methyl-
MCHM
34885-03-5 IND/SYN GAV HSD 09/14A
Methyleugenol
1,2-Dimethoxy-4-(2-propenyl)benzene
93-15-2 FOOD/NATL GAV HSD 04/17A
Microbiome
MICROBIOME NATL N/A 07/15A
Nanoscale Silver
Silver
7440-22-4 TBCO/NATL GAV 44 09/11A
Phenolic Benzotriazoles (Octrizole)
2-(2H-Benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol
PBZT
3147-75-9 IND GAV HSD 01/16A
Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade)]
Benzene, 1,1'-oxybis-, pentabromo deriv. (9CI)
DE 71
DE71
Pentabromodiphenyl oxide
Pentabromophenoxybenzene
32534-81-9 FLAM/SYN GAV HSD 11/16A
Perfluorohexane sulfonate potassium salt (PFHSKslt)
Perfluorohexane-1-sulphonic acid - potassium salt
Potassium perfluorohexane-1-sulphonate
1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexane-1-su1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoroh exane-1-sulfonic
3871-99-6 PLAS/SYN GAV HSD 02/12A
Perfluorooctanoic Acid
C8 Carboxylic acid
Pentadecafluorooctanoic acid (9CI)
PFOA
335-67-1 ELEC/SYN GAV HSD 04/17A
Phenolic Benzotriazoles (2-(2H-Benzotriazol-2-yl)phenol)
PBZT
Phenolic Benzotriazole
10096-91-0 ADHS GAV HSD 01/16A
Phenolic Benzotriazoles (2-(2H-benzotriazol-2-yl)-4,6-bis(1,1-dimethylpropyl)phenol)
PBZT
Phenol, 2-(2H-benzotriazol-2-yl)-4,6-bis(1,1-dimethylpropyl)-
25973-55-1 PEST GAV HSD 01/16A
Phenolic Benzotriazoles (2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol)
PBZT
Phenol, 2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)-
70321-86-7 IND GAV HSD 01/16A
Phenolic Benzotriazoles (2-(5-Chloro-2H-benzotriazol-2-yl)-4,6-bis(1,1-dimethylethyl)phenol)
2,4-Di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol
PBZT
3864-99-1 IND GAV HSD 01/16A
Phenolic Benzotriazoles (Bumetrizole)
2-(2-Hydroxy-3-tert-butyl-5-methylphenyl)-5-chloro-2H-benzotriazole
PBZT
3896-11-5 IND GAV HSD 02/16A
Propylene glycol phenyl ether
PPh
770-35-4 SOLV/SYN GAV HSD 09/14A
Pulegone
Cyclohexanone, 5-methyl-2-(1-methylethylidene)-,R-(9CI)
p-Menth-4(8)-en-3-one, R-(+)- (8CI)
(+)-R-Pulegone
89-82-7 DIET/N/S GAV HSD 03/17A
Sodium Metavanadate
Sodium metavanadate
13718-26-8 COMT/SYN WATER M3 HSD 10/14A 01/16A
2-ethylhexyl-2,3,4,5-tetrabromobenzoate
Benzoic acid, 2,3,4,5-tetrabromo-, 2-ethylhexyl ester
Flame Retardant 2
TBB
183658-27-7 ENVH/SYN GAV HSDE 11/16A
Tetrabromobisphenol A
Phenol, 4,4'-(1-methylethylidene)bis(2,6-dibromo (9CI)
TBBPA
79-94-7 FLAM GAV HSD 11/16A
2,2',4,4'-Tetrabromodiphenyl Ether
BDE-47
Benzene,1,1'-oxybis(2,4-dibromo)-(9CI)
DE-47
Flame Retardant 2
PBDE 47
5436-43-1 ENVH/SYN GAV HSDE 11/16A
Bis(2-ethylhexyl) tetrabromophthalate
1,2-Benzenedicarboxylic acid, 3,4,5,6-tetrabromo-, 1,2-bis(2- ethylhexyl) ester
Flame Retardant 2
TBPH
26040-51-7 PLAS/SYN GAV HSDE 11/16A
3,3',4,4'-Tetrachloroazobenzene
Diazene, bis(3,4-dichlorophenyl)- (9CI)
TCAB
14047-09-7 PEST/SYN GAV HSD 11/16A
Triclosan
2,4,4-Trichloro-2-hydroxydiphenyl ether
3380-34-5 COSM/SYN GAV HSD 11/16A
1,2,4-trimethylbenzene
C9 Alkylbenzenes
95-63-6 DYE INHAL M22 HSD 01/17A
Trimethylsilyldiazomethane (TMSD)
Diazomethyltrimethyl silane
Diazo((trimethylsilyl))methane
18107-18-1 REAG/SYN INHAL M3 HSD 10/15A
Triphenyl Phosphate
Flame Retardant 1
Phosphoric acid, triphenyl ester (9CI)
TPP
115-86-6 FLAM/SYN FEED M22 02/15A
Tris(Chloropropyl)phosphate
2-Propanol, 1-chloro-, phosphate (3:1) (9CI)
TCPP
Tris(2-chloroisopropyl)phosphate
13674-84-5 PEST GAV HSD 03/17A
Valerian (Valeriana officinalis L.) root extract
Valerian extract, powdered
8057-49-6 DIET/NATL GAV M22 09/15A
Vanadyl sulfate
Vanadium, oxo(sulfato(2-)-O)-
27774-13-6 DYE WATER M3 M22 HSD 09/14A 04/16A
Water disinfection byproducts (Bromodichloroacetic Acid)
Dichlorobromoacetic acid (Water disinfection byproducts)
71133-14-7 ENVH/NATL GAV HSD 04/17A
(A)CTUAL OR (E)STIMATED DATES.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.