National Toxicology Program

ToxFX is an automated toxicogenomics analysis application. The ToxFX analytical approach utilizes toxicogenomic signatures, specially-curated biochemical pathways and other relevant data to interpret toxicity-related transcriptomic data in minutes and presents the results as a detailed, customized report. This report is intended to improve your understanding of compound toxicity.

The ToxFX report can be produced from data generated from either Affymetrix GeneChip® Rat Genome 230 2.0 arrays or reduced feature set Affymetrix GeneChip® Rat ToxFX 1.0 arrays. The ToxFX 1.0 array contains customized content based on the NTP DrugMatrix® reference database. All that is required for data upload is PLIER normalized .chp files. Please note, uploaded data are not accessible to other users.

For individuals not familiar with ToxFX, a detailed user manual can be found on the “Documentation” page following log in.

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