National Toxicology Program

National Toxicology Program

UPDATE NewsletterUPDATE NewsletterMarch 2016

Teratology Society recognizes Kleinstreuer

By Catherine Sprankle
Reprinted from Environmental Factor

The Teratology Society will honor Nicole Kleinstreuer, Ph.D., deputy director of the National Toxicology Program Interagency Center for the Evaluation of Toxicological Methods (NICEATM), with the 2016 F. Clarke Fraser New Investigator Award.

The society will present the award during its June annual meeting in San Antonio. Kleinstreuer will give a plenary presentation about her research on mathematical and computational modeling of biological systems, and the susceptibility of those systems to disturbances that lead to adverse health outcomes. She will also co-chair a workshop on identifying developmental toxicants that can serve as references for validating alternative assays.

The award is given each year to recognize a Teratology Society member who has, within 10 years of completing training, established a successful independent research career in a field relevant to developmental biology.

Expertise to support a new direction in toxicology testing

The science of toxicology is relying more on mathematical and computational approaches that draw conclusions from large datasets generated by high throughput technologies. As an  expert in this area, Kleinstreuer began working with NICEATM in 2013 as a contractor with ILS, where she led the computational toxicology group.

Before joining ILS, Kleinstreuer completed postdoctoral training at the U.S. Environmental Protection Agency National Center for Computational Toxicology. Much of her work there involved developing predictive models of how environmental chemicals affect prenatal development.

In January, Kleinstreuer joined NIEHS as the NICEATM deputy director. In this role, she will continue to lead computational toxicology projects, interact with U.S. and international partners and stakeholders, and serve as a member of the Interagency Coordinating Committee on the Validation of Alternative Methods.

(Catherine Sprankle is a communications specialist for ILS, the contractor supporting NICEATM.)



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