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National Toxicology Program

National Toxicology Program

UPDATE NewsletterUPDATE NewsletterJune 2016

ICCVAM forum highlights recent activities and future plans

By Catherine Sprankle

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) held its annual public forum May 25 at the National Institutes of Health in Bethesda, Maryland. Representatives from ICCVAM member agencies were joined by attendees representing stakeholder groups, and over 100 webcast viewers. NICEATM organized the forum on behalf of ICCVAM.

Agency representatives presented updates on ICCVAM and ICCVAM member agency activities related to the development and validation of test methods and approaches that may replace, reduce, or refine animal use. Presenters from stakeholder groups praised recent progress made by ICCVAM and its member agencies towards replacing required animal tests with non-animal alternatives, and suggested future activities and areas that should receive increased focus.

NICEATM Director Warren Casey, Ph.D., described initial efforts towards developing a U.S. roadmap for replacement of animal use, and invited stakeholder participation in the effort. He described the roadmap as critical to ensuring that current efforts to develop non-animal testing systems, such as organs-on-a-chip, result in meaningful reductions in animal use. Development of the roadmap will be the main focus of the September meeting of ICCVAM’s advisory group, the Scientific Advisory Committee on Alternative Toxicological Methods.

ICCVAM, which is supported by NICEATM, is composed of representatives from sixteen U.S. Federal regulatory and research agencies that require, use, generate, or disseminate toxicological and safety testing information. ICCVAM was established to coordinate efforts within the federal government to promote new test methods and approaches that replace, reduce, or refine animal use, and to ensure those methods meet the needs of federal agencies.

Presentations from the public forum and a link to a recording of the webcast are available on the NICEATM website.

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Director of Office of Liaison, Policy, and Review and Editor-in-Chief: Mary Wolfe | Managing Editor: Anna Lee Mosley