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National Toxicology Program

National Toxicology Program

UPDATE NewsletterUPDATE NewsletterMay 2017

NTP Interagency Center for the Evaluation of Alternative Toxicological Methods

By Catherine Sprankle

ICCVAM to hold public forum May 23

Registration is open to attend the May 23 ICCVAM Public Forum to be held at the National Institutes of Health in Bethesda, Maryland.

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) is an interagency committee supported by NICEATM. ICCVAM holds annual public forums to share information and facilitate direct communication of ideas and suggestions from stakeholders. ICCVAM agencies will give presentations on their activities relevant to the ICCVAM mission. This year’s forum will also provide an opportunity for stakeholder input on an effort to establish a U.S. national strategy to explore new approaches for evaluating the safety of chemicals and medical products in the United States.

More information about the public forum and links to register to attend in person or view the webcast are available on the NICEATM website. Those planning to attend in person are encouraged to register by May 12.

NICEATM scientists support U.S. outreach to China

David Allen, Ph.D., principal investigator on the NICEATM support contract, joined other U.S. government and nongovernmental organization representatives at several meetings last month in the Chinese province of Guangdong. The goals of the trip were to share information on U.S. efforts to implement alternatives to animal testing and to promote international cooperation in these efforts, which is critical to their success. China currently participates as an observer in the International Cooperation on Alternative Test Methods (ICATM), of which ICCVAM is a member.

  • At the April 8 “Workshop on Alternative Methods for Eye Irritation Testing of Cosmetics” in Zhuhai, Allen presented recent and ongoing efforts led by NICEATM and ICCVAM to replace the use of animals for eye irritation testing with in vitro and in silico approaches. His presentations emphasized the successful public-private partnerships established by NICEATM and ICCVAM on these projects.
  • Allen joined scientists from an U.S. in vitro research and testing laboratory at a meeting at the U.S. Consulate in Guangzhou to discuss barriers to trade due to current animal testing requirements for cosmetics in China. This meeting was followed by a visit to the Food Testing Laboratory of the Guangdong Inspection and Quarantine Technology Center to observe laboratories where required in vivo and in vitro toxicology testing is conducted.
  • At the Seventh Congress on Alternative Methods (April 12-14) in Guangzhou, Allen presented a summary of U.S. efforts to advance the practice of alternative test methods. This presentation, which Allen gave at the invitation of the U.S. Department of Commerce, emphasized the successful partnerships within the U.S. federal government through ICCVAM and the public-private partnerships that are ongoing between ICCVAM agencies and nongovernment stakeholders.

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The Update Newsletter is produced by NTP Office of Liaison, Policy, and Review. The text is not copyrighted and can be reprinted without permission. If you use parts of the Update Newsletter in your publication, we ask that you provide us with a copy for our records. We welcome your comments and suggestions.

Director of Office of Liaison, Policy, and Review and Editor-in-Chief: Mary Wolfe | Managing Editor: Anna Lee Mosley