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National Toxicology Program

National Toxicology Program

UPDATE NewsletterUPDATE NewsletterJanuary 2020

The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

By Catherine Sprankle

EPA updates list of alternative test methods and strategies

In December, the U.S. Environmental Protection Agency (EPA) released an update of its “List of Alternative Test Methods and Strategies (or New Approach Methodologies [NAMs])”. Creation and maintenance of this list was required by the Frank R. Lautenberg Chemical Safety for the 21st Century Act, passed in 2016 to update the Toxic Substances Control Act (TSCA). The list includes tests for human health effects, tests for effects on biotic systems, NAM-related EPA policies that may be relevant to TSCA, and other NAMs that may be used for TSCA. The updated list and other information about use of NAMs for TSCA are available on the EPA website.

EPA is a member agency of the Interagency Coordinating Committee on the Validation of Alternative Methods, which is supported by NICEATM.

NIEHS to provide small business funding for genetically diverse toxicity tests

The National Institute of Environmental Health Sciences (NIEHS) announces the availability of Small Business Innovation Research Grants to support the development of chemical testing resources and approaches that better reflect the genetic diversity among human populations. The resources and approaches might include panels of human cells or cell lines, panels of cell lines generated from genetically diverse rodent strains, lower organism strains with well-characterized genetic backgrounds, or in silico approaches to enhance the ability to characterize the effects of genetic variation in toxicity testing. These grants are available only to U.S. small businesses. Letters of intent are due January 19, with applications due February 19.

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The Update Newsletter is produced by NTP Office of Liaison, Policy, and Review. The text is not copyrighted and can be reprinted without permission. If you use parts of the Update Newsletter in your publication, we ask that you provide us with a copy for our records. We welcome your comments and suggestions.

Director of Office of Liaison, Policy, and Review and Editor-in-Chief: Mary Wolfe | Managing Editor: Anna Lee Mosley