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https://ntp.niehs.nih.gov/go/rocnom

Environmental Factors Under Consideration

Environmental factors include occupational and environmental exposures and exposure circumstances including those related to medical practice, modern light styles, natural and human-made sources. NTP is gathering information (e.g., preliminary literature searches) on these factors to determine whether it should conduct a formal cancer hazard evaluation or prepare other reports providing public health information related to cancer hazards. You can provide information such as citations, new studies, or scientific issues on any of the substances.

View the list of ongoing evaluations.

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NW
List of nominated topics
Topic CASRN Primary Uses or Exposures FRN Public Comments
A
B
C
Chlorothalonil and other pesticides (2,4,5,6-tetrachloro-isophthalonitrile) 1897-45-6 A broad-spectrum pesticide used on a variety of vegetable and orchard crops. It is also used as a mildewicide added to paint and other surfaces. September 20, 2013
(PDF HTML)
Public Comments
D
Diesel exhaust particulates

A mixture of combustion products of diesel fuel; the exact composition of the mixture depends on the nature of the engine, operating conditions, lubricating oil, additives, emission control system, and fuel composition. Occupational exposure occurs primarily among miners (who use diesel power equipment), railroad workers and transportation workers such as truck drivers.

First listed as Reasonably Anticipated to be a Human Carcinogen in the 12th RoC.

January 19, 2012
(PDF HTML)
Public Comments
E
F
Flame retardants
  • Pentabromodiphenyl ether mixture (DE-71)
  • Tetrabromobisphenol A (TBBPA)
  • Tris-(1,3-dichloro-2-propyl) phosphate (TDCPP)
32534-81-9
79-94-7
13674-87-8

Pentabromodiphenyl ether mixture (DE-71) is a flame retardant mixture used in furniture materials; voluntarily phased out in the United States in 2004. Widespread occurrence in the environment.

Tetrabromobisphenol A (TBBPA) is a brominated flame retardant used in circuit boards, to encapsulate electronics, and intermediate for other flame retardants.

TDCPP is an organophosphate flame retardant used in the polyurethane foam padding in furniture and automobiles.

October 7, 2015
(PDF HTML)
Public Comments
G - O
P
Pentabromodiphenyl ether mixture (DE-71) (see Flame retardants)
Perfluorooctanoic acid (PFOA) 335-67-1 Used in the manufacturing of fluoropolymers. Fluoropolymers are primarily used to provide non-stick to cookware and waterproof membranes for clothing. They are also used in other applications and have fire-resistance properties. September 20, 2013
(PDF HTML)
Public Comments
Q - S
T
Tetrabromobisphenol A (TBBPA) (see Flame retardants)
Tris-(1,3-dichloro-2-propyl) phosphate (TDCPP) (see Flame retardants)
U
W
Wood smoke Smoke from wood burning fireplaces and stoves. September 20, 2013
(PDF HTML)
Public Comments
V - Z

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