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https://ntp.niehs.nih.gov/go/HAAs

RoC Review of Haloacetic Acids Found as Water Disinfection By-Products

Glass of water with chemical formulas composited on top

Substance Overview

Status: Cancer hazard evaluation for potential listing in the Report on Carcinogens (RoC)

Primary Uses or Exposures

  • Derivatives of acetic acid with one or more halogen atoms (i.e., chlorine or bromine) attached that are formed during chlorination of water containing organic molecules.
  • People are mainly exposed to HAA from ingestion of chlorinated drinking water; they may also be exposed to HAAs from bathing or the use of swimming pools and spas that use chlorine for disinfection.
  • More than 250 million people receive disinfected water, with 98% of water treatment systems using some type of chlorine disinfection process. Water disinfection is among the most important and beneficial public health advances of the 20th century in the United States and worldwide.
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Documents

Documents for Haloacetic Acids
Date Document
Oct 07, 2015 Federal Register notice requesting public comment on nominated substances (PDF HTML)
Mar 01, 2016 RoC Concept
Mar 23, 2017 RoC Protocol
Jun 06, 2017 RoC Monograph - Peer review draft
Oct 30, 2017 RoC Monograph - Revised draft
Mar 30, 2018 RoC Monograph - Final (correction posted Feb. 23, 2021)
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Meetings & Events

Listing of related events
Date Event Event Type Materials
Apr 11, 2016

NTP Board of Scientific Counselors Meeting

Board of Scientific Counselors
  • Agenda
  • Meeting Materials

    NTP Board of Scientific Counselors Meeting Meeting Materials
    April 11, 2016

    Supplemental materials for events, meetings, and workshops prior to 2017 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials for the following meeting.

  • Minutes
Jul 24, 2017

Peer Review of the Draft RoC Monograph on Haloacetic Acids Found as Water Disinfection By-Products

 Expert Panels - RoC Monographs
Dec 07, 2017

NTP Board of Scientific Counselors Meeting

Board of Scientific Counselors

Supplemental materials for events, meetings, and workshops prior to 2017 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials for the following meeting.

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Public Comments

List of Public Comments for the Report on Carcinogens
Date Received Commenter(s) Affiliation In Response To
Apr 04, 2016 Judith Nordgren Chlorine Chemistry Division/American Chemistry Council Mar 14, 2016 Federal Register notice
Jul 11, 2017 Tasha Stoiber, Ph.D. Environmental Working Group Jun 23, 2017 Federal Register notice
Jul 14, 2017 Judith Nordgren Chlorine Chemistry Division/American Chemistry Council Jun 23, 2017 Federal Register notice
Nov 29, 2017 Judith Nordgren Chlorine Chemistry Division/American Chemistry Council Nov 09, 2017 Federal Register notice
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Note on Accessibility: Persons with disabilities or using assistive technology may find some documents are not fully accessible. For assistance, email us or use our contact form and identify the documents/pages for which access is required. We will assist you in accessing the content of these files. NIEHS has helpful information on accessibility.