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Testing Status of Ethylene glycol 2-ethylhexyl ether 08033

 

CASRN: 1559-35-9

Formula: C10-H22-O2

Synonyms/Common Names

  • EGEHE
  • Ethanol, 2-((2-ethylhexyl)oxy)-

Modified One-Generation

  • GD 6 to PND 28 Dose Range Finding (Gavage)  (MOG08033)  Completed 
    • Dose Range Finding
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 312.5, 625, 1250, or 2500 mg/kg/day.

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage)  (K08033)  Completed 
    • Citation: Watson ATD, Moeller BC, Doyle-Eisele M, Garner E, Blystone CR, McDonald JD, Waidyanatha S. Disposition and metabolism of ethylene glycol 2-ethylhexyl ether in Sprague Dawley rats, B6C3F1/N mice, and in vitro in rat hepatocytes. Xenobiotica. 2021 Jun;51(6):689-702. doi: https://doi.org/10.1080/00498254.2021.1898062. Epub 2021 Mar 26.Pubmed Abstract
    • Male and Female Rats: Harlan Sprague-Dawley; Male and Female Mice: B6C3F1/N
    • Dose: 150 mg/kg. 50, 150 or 500 mg/kg.