Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Chloroethane 10019-D

 

CASRN: 75-00-3

Formula: C2-H5-Cl

Synonyms/Common Names

  • Ethane, chloro-
  • Ethyl chloride

Short-Term Toxicity

  • 14-Day (Inhalation)  (C06224)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Inhalation)  (C06224)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 2500, 19000 PPM/10 PER GROUP.

Long-Term Carcinogenicity

  • 2 years (Inhalation)  (C06224)  Completed 
    • TR-346 (NIH Number: 90-2801)  (Peer Review Approval 10/03/1988A )
      Toxicology and Carcinogenesis Studies of Chloroethane (Ethyl Chloride) (CASRN 75-00-3) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Equivocal Evidence 
      • Female Rats Equivocal Evidence 
      • Male Mice Inadequate Study 
      • Female Mice Clear Evidence 
    • Dose: R&M: 0, 15000 PPM/50 PER GROUP.

Genetic Toxicology

  • Micronucleus  (A92751)  Completed 
    • Mice: B6C3F1
    • Male Not a Valid Test 
  • Salmonella  (306504)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Positive