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Testing Status of Sodium azide 10164-D

 

CASRN: 26628-22-8

Formula: N3-Na

Synonyms/Common Names

  • Hydrazoic acid, sodium salt

Short-Term Toxicity

  • 14-Day (Gavage)  (C06462)  Completed 
    • Rats: F344/N
  • 13-Week (Gavage)  (C06462)  Completed 
    • Rats: F344/N
    • Dose: RATS ONLY:0, .063, 4 MG/ML/10 PER GROUP.

Long-Term Carcinogenicity

  • 2 years (Gavage)  (C06462)  Completed 
    • TR-389 (NIH Number: 91-2844)  (Peer Review Approval 04/25/1990A )
      Toxicology and Carcinogeneis Studies of Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage Studies)
    • Rats: F344/N
    • Carcinogenesis Results
      • Male Rats No Evidence 
      • Female Rats No Evidence 
    • Dose: RATS ONLY:0, 5, 10 MG/KG/60 PER GROUP.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (166603)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Salmonella  (201201)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Positive 
  • Salmonella  (A90612)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    •  Positive 
  • Salmonella  (G10164)  Completed 
    •  Positive 
  • Salmonella  (N-9164)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol Environ. Mutagen. Vol. 6 (Suppl 2) (1984) 1-251