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Styrene (100-42-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2021284


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Negative, Male, Rats
View
  • Negative, Female, Rats

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Styrene (100-42-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Styrene (100-42-5).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Styrene (100-42-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-185 Bioassay of Styrene for Possible Carcinogenicity (CASRN100-42-5)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C02200B) of Styrene (100-42-5) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C02200B) of Styrene (100-42-5) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C02200B) of Styrene (100-42-5) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C02200B) of Styrene (100-42-5) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity of Styrene (100-42-5) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Styrene (100-42-5) in Female F344 Rats Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Styrene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 173117
Summary Data