Testing Status of C.I. Pigment Red 23 10210-D
CASRN: 6471-49-4
Formula: C24-H17-N5-O7
Synonyms/Common Names
- 3-Hydroxy-4-((2-methoxy-5-nitrophenyl)azo)-N-(3-nitrophenyl)naphthalene-2-carboxamide
- Red 23, C.I. Pigment
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C60377)
Completed
- Rats: F344/N; Mice: B6C3F1
- 13-Week (Dosed-Feed)
(C60377)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: R&M: 0, 3000, 6000, 12500, 25000, 50000 PPM (10 PER GROUP).
Long-Term Carcinogenicity
- 2 years (Dosed-Feed)
(C60377)
Completed
- TR-411 (NIH Number: 93-3142)
(Peer Review Approval 03/11/1991A )
Toxicology and Carcinogenesis Studies of C.I. Pigment Red 23 (CASRN 6471-49-4) in F344 Rats and B6C3F1 Mice (Feed Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Equivocal Evidence
- Female Rats No Evidence
- Male Mice No Evidence
- Female Mice No Evidence
- Dose: R&M: 0, 10000, 25000, 50000 PPM (60 PER GROUP).
- TR-411 (NIH Number: 93-3142)
(Peer Review Approval 03/11/1991A )
Special Studies
- Absorption Disposition Metabolism Elimination (Gavage)
(S0031)
Completed
- Citation: El Dareer SM, Tillery KF, Hill DL. Investigations on the disposition of oral doses of some water-insoluble pigments. Bull Environ Contam Toxicol. 1984 Feb;32(2):171-4.Pubmed Abstract
- Rats
- Dose: 5.2 MG/KG.
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(115073)
Completed
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Negative
- Salmonella
(721735)
Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Positive