Testing Status of Propiolactone 10370-F

CASRN: 57-57-8

Formula: C3-H4-O2

Synonyms/Common Names

• 2-Oxetanone (9CI)

Genetic Toxicology

• Drosophila  (024474)  Completed 
  • Citation: Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: I. Comparison of positive and negative control data for sex-linked recessive lethal mutations and reciprocal translocations in three laboratories Environ. Mutagen. Vol. 6 (1984) 189-202
  • Sex-Linked Recessive Lethal Positive 
  • Reciprocal Translocation Positive 
• Drosophila  (232716)  Completed 
  • Sex-Linked Recessive Lethal Positive 
  • Reciprocal Translocation Positive 
• Drosophila  (377603)  Completed 
  • Reciprocal Translocation/Sex-Linked Recessive Lethal Positive 
• Drosophila  (409489)  Completed 
  • Sex-Linked Recessive Lethal Positive 
  • Reciprocal Translocation Positive 
• Drosophila  (521474)  Completed 
  • Citation: Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: I. Comparison of positive and negative control data for sex-linked recessive lethal mutations and reciprocal translocations in three laboratories Environ. Mutagen. Vol. 6 (1984) 189-202
  • Sex-Linked Recessive Lethal Positive 
  • Reciprocal Translocation Positive 
• Drosophila  (824474)  Completed 
  • Citation: Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: I. Comparison of positive and negative control data for sex-linked recessive lethal mutations and reciprocal translocations in three laboratories Environ. Mutagen. Vol. 6 (1984) 189-202
  • Sex-Linked Recessive Lethal Positive 
  • Reciprocal Translocation Positive 
• Drosophila  (831466)  Completed 
  • Reciprocal Translocation/Sex-Linked Recessive Lethal Positive 
• Drosophila  (935061)  Completed 
  • Sex-Linked Recessive Lethal Positive 
  • Reciprocal Translocation Positive 
• In Vitro Cytogenetics (CA/SCE)  (029474)  Completed 
  • Citation: Galloway, S., Bloom, A., Resnick, M., Margolin, B., Nakamura, F., Archer, P., and Zeiger, E. Development of a standard protocol for in vitro cytogenetic testing with CHO cells: Comparison of results for 22 compounds in two laboratories. Environ. Mutagen. Vol. 7 (1985) 1-52
  • Sister Chromatid Exchange Positive 
  • Chromosome Aberrations Positive 
• In Vitro Cytogenetics (CA/SCE)  (925474)  Completed 
  • Citation: Galloway, S., Bloom, A., Resnick, M., Margolin, B., Nakamura, F., Archer, P., and Zeiger, E. Development of a standard protocol for in vitro cytogenetic testing with CHO cells: Comparison of results for 22 compounds in two laboratories. Environ. Mutagen. Vol. 7 (1985) 1-52
  • Sister Chromatid Exchange Positive 
  • Chromosome Aberrations Weakly Positive 
• Salmonella  (093841)  Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Positive 
• Salmonella  (243815)  Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Positive 
• Salmonella  (272799)  Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Positive 
• Salmonella  (573799)  Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Positive 
• Salmonella  (681407)  Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Positive