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Aniline (62-53-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8020090


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Aniline (62-53-3).
Micronucleus - Mice
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  • Male: Positive
    Female: Positive
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Aniline (62-53-3).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Aniline (62-53-3).
Mammalian Cell Cytogenetics
CA SCE
  • View
    • Weakly Positive
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Aniline (62-53-3).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Aniline (62-53-3).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Aniline (62-53-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Ress NB, Witt KL, Xu J, Haseman JK, Bucher JR. Micronucleus induction in mice exposed to diazoaminobenzene or its metabolites, benzene and aniline: implications for diazoaminobenzene carcinogenicity. Mutation Res. Vol. 521 (2002) 201 - 208
McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219
Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 349-367
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of Aniline (62-53-3) in Micronucleus Study A17175 in B6C3F1 Mice
Genetic Toxicity Evaluation of Aniline (62-53-3) in Micronucleus Study A29061 in B6C3F1 Mice
Genetic Toxicity Evaluation of Aniline in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 712474
Summary Data