D-Mannitol (69-65-8)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1023235
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Rodent Cytogenetics |
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CA |
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Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity |
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SLRL |
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Bacterial Mutagenicity |
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Publications
TR-236
Carcinogenesis Bioassay of D-Mannitol (CASRN 69-65-8) in F344/N Rats and B6C3F1 Mice (Feed Study)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
Myhr, B. and Caspary, W. Chemical mutagenesis at the TK locus in L5178Y mouse lymphoma cells. I. Results for 31 coded compounds in the National Toxicology Program. Environ. Molec. Mutagen. Vol. 18 (1991) 51-83
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of D-Mannitol (69-65-8) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of D-Mannitol (69-65-8) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of D-Mannitol (69-65-8) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of D-Mannitol (69-65-8) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of D-Mannitol (69-65-8) in Micronucleus Study 090264 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of D-Mannitol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 315204
Summary Data
- G06 - Ames Summary Data (130 KB)
Genetic Toxicity Evaluation of D-Mannitol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 379044
Summary Data
- G06 - Ames Summary Data (128 KB)
Genetic Toxicity Evaluation of D-Mannitol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 514632
Summary Data
- G06 - Ames Summary Data (134 KB)
Genetic Toxicity Evaluation of D-Mannitol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 527050
Summary Data
- G06 - Ames Summary Data (138 KB)