Testing Status of o-Phenylphenol 10439-P

CASRN: 90-43-7

Formula: C12-H10-O

Synonyms/Common Names

• (1,1'-Biphenyl)-2-ol (9CI)

Short-Term Toxicity

• 14-Day (Topical Application)  (C50351)  Completed 
  • Mice: Swiss

Long-Term Carcinogenicity

• 2 years (Topical Application)  (C50351)  Completed 
  • TR-301 (NIH Number: 86-2557)  (Peer Review Approval 03/29/1985A )
    Toxicology and Carcinogenesis Studies of ORTHO-Phenylphenol (CASRN 90-43-7) Alone and with 7,12-Dimethylbenz(a)anthracene (CASRN 57-97-6) in Swiss CD-1 Mice (Dermal Studies)
  • Mice: Swiss
  • Carcinogenesis Results
    • Male Mice No Evidence 
    • Female Mice No Evidence 
  • Dose: 55.5 MG/0.1 ML/50 PER GROUP.

Genetic Toxicology

• Drosophila  (589891)  Completed 
  • Citation: Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
  • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
• In Vitro Cytogenetics (CA/SCE)  (913440)  Completed 
  • Sister Chromatid Exchange Weakly Positive 
  • Chromosome Aberrations Negative 
• Mouse Lymphoma  (550257)  Completed 
  • Mice
  •  Positive 
• Mouse Lymphoma  (904368)  Completed 
  • Mice
  •  Positive 
• Salmonella  (470644)  Completed 
  •  Negative 
• Salmonella  (747588)  Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Weakly Positive