U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

5-Chloro-o-toluidine (95-79-4)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5020287


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Negative, Female, Rats

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 5-Chloro-o-toluidine (95-79-4).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 5-Chloro-o-toluidine (95-79-4).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 5-Chloro-o-toluidine (95-79-4).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative
View
  • Negative

Citation Information


NTP. 5-Chloro-o-toluidine (95-79-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-187 Bioassay of 5-Chloro-o-toluidine for Possible Carcinogenicity (CASRN 95-79-4)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 5-Chloro-o-toluidine (95-79-4) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 5-Chloro-o-toluidine (95-79-4) in Female F344 Rats Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 5-Chloro-o-toluidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 092475
Summary Data
Genetic Toxicity Evaluation of 5-Chloro-o-toluidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 729677
Summary Data
Genetic Toxicity Evaluation of 5-Chloro-o-toluidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 763573
Summary Data