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Testing Status of Methylenedianiline 10489-E

 

CASRN: 101-77-9

Formula: C13-H14-N2

Synonyms/Common Names

  • 4,4'-Methylenebis-benzenamine (9CI)

Genetic Toxicology

  • Chromosome Aberrations  (535562)  Completed 
    • Mice
    •  Positive 
  • In Vitro Cytogenetics (CA/SCE)  (321885)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Micronucleus  (129952)  Completed 
    • Citation: Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
    • Mice: B6C3F1
    • Male Positive (Nonstandard Protocol) 
  • Salmonella  (320619)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Positive 
  • Sister Chromatid Exchanges  (535562)  Completed 
    • Mice
    • Sister Chromatid  Positive