Testing Status of Allyl chloride 10516-S
CASRN: 107-05-1
Formula: C3-H5-Cl
Synonyms/Common Names
- 3-Chloro-1-propene
Short-Term Toxicity
- 14-Day (Gavage)
(C04615)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- 13-Week (Gavage)
(C04615)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0, 56, 562, M: 0, 178, 1780 MG/KG/5 PER GROUP.
Long-Term Carcinogenicity
- 2-Year (Gavage)
(C04615)
Completed
- TR-073 (NIH Number: 78-1323)
(Peer Review Approval 06/29/1978A )
Bioassay of Allyl Chloride for Possible Carcinogenicity (CASRN 107-05-1) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Equivocal
- Female Mice Equivocal
- Dose: FR: 0, 55, 73 (AVG), MR: 0, 57, 77 (AVG), FM: 0, 129, 258 (AVG), MM: 0, 172, 199 (AVG) MG/KG/50 PER GROUP.
- TR-073 (NIH Number: 78-1323)
(Peer Review Approval 06/29/1978A )
Genetic Toxicology
- Salmonella
(096311)
Completed
- Citation: McGregor, D.B., Reynolds, D.M., and Zeiger, E. Conditions affecting the mutagenicity of trichloroethylene in Salmonella Environ. Molec. Mutagen. Vol. 13 (1989) 197-202
- Positive
Organ Systems Toxicity
- 7 to 14 GD Short-Term in vivo Repro. Tox. (Gavage)
(T0057)
Completed
- Citation: Screening of Priority Chemicals for Reproductive Hazards
- Female Mice: Swiss
- Dose: 500 MG/KG BODY WEIGHT.