2,4-Dinitrotoluene (121-14-2)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020529
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity | |
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SLRL | RT |
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Bacterial Mutagenicity |
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Publications
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
Loveday, K.S., Lugo, M.H., Resnick, M.A., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro II: Results with 20 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 60-94
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Dinitrotoluene (121-14-2) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Dinitrotoluene (121-14-2) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Dinitrotoluene (121-14-2) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Dinitrotoluene (121-14-2) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Cytogenetic Study of 2,4-Dinitrotoluene in Chinese Hamster Ovary Cell Sister Chromatid Exchange Test
Genetic Toxicity Evaluation of 2,4-Dinitrotoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 683014
Summary Data
- G06 - Ames Summary Data (100 KB)