Testing Status of Propyl gallate 10564-Y
CASRN: 121-79-9
Formula: C10-H12-O5
Synonyms/Common Names
- 3,4,5-Trihydroxybenzoic acid propylester (9CI)
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C50588)
Completed
- Rats: F344/N; Mice: B6C3F1
- 13-Week (Dosed-Feed)
(C50588)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: R: 0, 1500, 25000, M: 0, 800, 12500 PPM/10 PER GROUP.
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C50588)
Completed
- TR-240 (NIH Number: 82-1796)
(Peer Review Approval 12/16/1981A )
Carcinogenesis Bioassay of Propyl Gallate (CASRN 121-79-9) in F344/N Rats and B6C3F1 Mice (Feed Study) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Equivocal
- Female Rats Negative
- Male Mice Equivocal
- Female Mice Negative
- Dose: 0, 6000, 12000 PPM/50 PER GROUP.
- TR-240 (NIH Number: 82-1796)
(Peer Review Approval 12/16/1981A )
Genetic Toxicology
- Chromosome Aberrations
(299865)
Completed
- Citation: Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313
- Mice
- Positive
- Drosophila
(677217)
Completed
- Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
- Reciprocal Translocation/Sex-Linked Recessive Lethal Equivocal
- In Vitro Cytogenetics (CA/SCE)
(257022)
Completed
- Citation: Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Positive
- Micronucleus
(512803)
Completed
- Citation: Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
- Mice: B6C3F1
- Male Negative
- Micronucleus
(A73992)
Completed
- Mice: B6C3F1
- Male Positive
- Mouse Lymphoma
(099874)
Completed
- Citation: McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
- Mice
- Positive
- Salmonella
(985325)
Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Negative
- Sister Chromatid Exchanges
(299865)
Completed
- Citation: Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313
- Mice
- Sister Chromatid Negative (Nonstandard Protocol)