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Testing Status of Formulated fenaminosulf 10593-T

 

CASRN: 140-56-7

Formula: C8-H11-N3-O3-S.Na

Synonyms/Common Names

  • (4-(Dimethylamino)phenyl)diazenesulfonic acid, sodium salt (9CI)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C03010)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C03010)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, .008, .060 %/10 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C03010)  Completed 
    • TR-101 (NIH Number: 78-1351)  (Peer Review Approval 04/26/1978A )
      Bioassay of Formulated Fenaminosulf for Possible Carcinogenicity (CASRN 140-56-7)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Negative 
      • Male Mice Negative 
      • Female Mice Negative 
    • Dose: R&FM: 0, .05, .10 (AVG), MM: 0, .10, .19 (AVG) %/50 PER GROUP.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (386052)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Mouse Lymphoma  (321970)  Completed 
    • Mice
    •  Positive 
  • Salmonella  (136878)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Positive