Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Aniline hydrochloride 10596-F

 

CASRN: 142-04-1

Formula: C6-H7-N.Cl-H

Synonyms/Common Names

  • ''aniline Salt''
  • Anilinium chloride
  • Benzenamine, hydrochloride
  • Phenylamine hydrochloride
  • Phenylammonium chloride

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C03736)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C03736)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 0.03, 1.0 %/5 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C03736)  Completed 
    • TR-130 (NIH Number: 78-1385)  (Peer Review Approval 06/29/1978A )
      Bioassay of Aniline Hydrochloride for Possible Carcinogenicity (CASRN 142-04-1)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Positive 
      • Female Rats Positive 
      • Male Mice Negative 
      • Female Mice Negative 
    • Dose: R: 0, .3, .6, M: 0, .6, 1.2 %/50 PER GROUP.

Genetic Toxicology

  • Salmonella  (N-9372)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol Environ. Mutagen. Vol. 6 (Suppl 2) (1984) 1-251