Testing Status of Sodium diethyldithiocarbamate 10597-J
CASRN: 148-18-5
Formula: C5-H11-N-S2.Na
Synonyms/Common Names
- Diethylcarbamodithioic acid sodium salt (9CI)
Short-Term Toxicity
- 13 weeks (Dosed-Feed)
(C02835)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: R: 0, 1250, 40000, M: 0, 2500, 10000 PPM/5 PER GROUP.
Long-Term Carcinogenicity
- 2 years (Dosed-Feed)
(C02835)
Completed
- TR-172 (NIH Number: 79-1728)
(Peer Review Approval 12/13/1978A )
Bioassay of Sodium Diethyldithiocarbamate for Possible Carcinogenicity (CASRN 148-18-5) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: R: 0, 1250, 2500, M: 0, 500, 4000 PPM/50 PER GROUP.
- TR-172 (NIH Number: 79-1728)
(Peer Review Approval 12/13/1978A )
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(552900)
Completed
- Citation: Loveday, K.S., Lugo, M.H., Resnick, M.A., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro II: Results with 20 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 60-94
- Sister Chromatid Exchange Negative
- Chromosome Aberrations Negative
- Mouse Lymphoma
(456551)
Completed
- Citation: McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219
- Mice
- Positive
- Salmonella
(965008)
Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Negative