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Testing Status of Pentachlorobenzene 10646-W

 

CASRN: 608-93-5

Formula: C6-H-Cl5

Synonyms/Common Names

  • Benzene, pentachloro- (8CI)(9CI)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C61847A)  Completed 
    • TOX-06 (NIH Number: 91-3125)  (Peer Review Approval 11/21/1989A )
      Toxicity Studies of Pentachlorobenzene in F344/N Rats and B6C3F1 Mice (Feed Studies) (CASRN 608-93-5)
    • Rats: F344/N; Mice: B6C3F1
  • 13 weeks (Dosed-Feed)  (C61847A)  Completed 
    • TOX-06 (NIH Number: 91-3125)
      Toxicity Studies of Pentachlorobenzene in F344/N Rats and B6C3F1 Mice (Feed Studies) (CASRN 608-93-5)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 33, 100, 330, 1000, 2000 PPM.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (710481)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Micronucleus  (A72140)  Completed 
    • Citation: Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative 
  • Salmonella  (187994)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Negative