2,6-Dichloro-p-phenylenediamine (609-20-1)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7020427
Study Results
Chronic Bioassay Level of Evidence
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Mice | |
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Genetic Toxicology
Rodent Cytogenetics | |
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CA | SCE |
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Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity |
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SLRL |
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Bacterial Mutagenicity |
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Publications
TR-219
Carcinogenesis Bioassay of 2,6-Dichloro-p-Phenylenediamine (CASRN 609-20-1) in F344 Rats and B6C3F1 Mice (Feed Study)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Micronucleus Study 538041 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2,6-Dichloro-p-phenylenediamine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 010183
Summary Data
- G06 - Ames Summary Data (50 KB)
Genetic Toxicity Evaluation of 2,6-Dichloro-p-phenylenediamine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 949384
Summary Data
- G06 - Ames Summary Data (174 KB)