Testing Status of Hexamethylphosphoramide 10658-L
CASRN: 680-31-9
Formula: C6-H18-N3-O-P
Synonyms/Common Names
- Hexamethylphosphoric triamide (9CI)
Genetic Toxicology
- Chromosome Aberrations
(A48570)
Completed
- Mice
- Positive (Nonstandard Protocol)
- Drosophila
(609861)
Completed
- Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
- Sex-Linked Recessive Lethal Positive
- Reciprocal Translocation Positive
- In Vitro Cytogenetics (CA/SCE)
(088581)
Completed
- Citation: Gulati, D., Sabharwal, P., and Shelby, M. Tests for the induction of chromosomal aberrations and sister chromatid exchanges in cultured Chinese hamster ovary (CHO) cells. In Evaluation of Short-Term Tests for Carcinogens, Elsevier/North Holland 413-426
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Negative
- Mouse Lymphoma
(304965)
Completed
- Citation: Myhr, B., Bower, L., and Caspary, W. Assays for the induction of gene mutations at the thymine kinase locus in L1578Y mouse lymphoma cells in culture. In Evaluation of Short-Term Tests for Carcinogens, Elsevier/North Holland Vol. (1985) 555-568
- Mice
- Positive
- Salmonella
(753161)
Completed
- Citation: Zeiger, E., and Haworth, S. Tests with a preincubation modification of the Salmonella/microsome assay. In Evaluation of Short-Term Tests for Carcinogens Elsevier/North Holland 187-199
- Negative
Organ Systems Toxicity
- Total Reproductive Capacity (Gavage)
(TRC98019)
Completed
- Citation: Bishop, JB, Morris, RW, Seely, JC, Hughes, LA, Cain, KT, Generoso, WM. Alterations in the Reproductive Patterns of Female Mice Exposed to Xenobiotics. Fund. and Appl. Tox. 40: 191-204 (1997).
- Female Mice
- Mice Female +, INTERVAL 1
- +, INTERVAL 1