Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Dibutyltin diacetate 10670-W

 

CASRN: 1067-33-0

Formula: C12-H24-O4-Sn

Synonyms/Common Names

  • Bis(acetyloxy)dibutylstannane

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C02028)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C02028)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0, 70, 315, M: 0, 17, 650 PPM/5 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C02028)  Completed 
    • TR-183 (NIH Number: 79-1739)  (Peer Review Approval 10/25/1978A )
      Bioassay of Dibutyltin Diacetate for Possible Carcinogenicity (CASRN 1067-33-0)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Inadequate Study 
      • Male Mice Negative 
      • Female Mice Negative 
    • Dose: R: 0, 66.5, 133 (AVG), M: 0, 76, 152 (AVG) PPM/50 PER GROUP.

Genetic Toxicology

  • Drosophila  (373936)  Completed 
    • Citation: Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
    • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
  • In Vitro Cytogenetics (CA/SCE)  (092968)  Completed 
    • Sister Chromatid Exchange Weakly Positive 
    • Chromosome Aberrations Positive 
  • Mouse Lymphoma  (881018)  Completed 
    • Mice
    •  Positive 
  • Salmonella  (834817)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative