Testing Status of Iodinated glycerol 10733-G
CASRN: 5634-39-9
Formula: C6-H11-I-O3
Synonyms/Common Names
- 2-(1-Iodoethyl)-1,3-dioxolane-4-methanol (9CI)
Short-Term Toxicity
- 14-Day (Gavage)
(C55469)
Completed
- Rats: F344/N; Mice: B6C3F1
- 13-Week (Gavage)
(C55469)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: 0, 0.31, 0.5 G/KG/10 PER GROUP.
Long-Term Carcinogenicity
- 109 weeks (Gavage)
(C55469)
Completed
- TR-340 (NIH Number: 90-2596)
(Peer Review Approval 10/04/1988A )
Toxicology and Carcinogenesis Studies of Iodinated Glycerol (Organidin®) (CASRN 5634-39-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Some Evidence
- Female Rats No Evidence
- Male Mice No Evidence
- Female Mice Some Evidence
- Dose: FR&FM: 0, 62, 125, MR&MM: 0, 125, 250 MG/KG/50 PER GROUP.
- TR-340 (NIH Number: 90-2596)
(Peer Review Approval 10/04/1988A )
Genetic Toxicology
- Drosophila
(662601)
Completed
- Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
- Reciprocal Translocation/Sex-Linked Recessive Lethal Negative
- In Vitro Cytogenetics (CA/SCE)
(773890)
Completed
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Weakly Positive
- Micronucleus
(985532)
Completed
- Mice: B6C3F1
- Male Negative
- Mouse Lymphoma
(616705)
Completed
- Mice
- Positive
- Salmonella
(139180)
Completed
- Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
- Positive