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Testing Status of 2-Chloro-p-phenylenediamine sulfate 10801-F

 

CASRN: 61702-44-1

Formula: C6-H7-Cl-N2.H2-O4-S

Synonyms/Common Names

  • 2-Chloro-1,4-benzenediamine sulfate (1:1)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C03316)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C03316)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, .03, 3.0 %/5 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C03316)  Completed 
    • TR-113 (NIH Number: 78-1368)  (Peer Review Approval 04/26/1978A )
      Bioassay of 2-Chloro-p-phenylenediamine Sulfate for Possible Carcinogenicity (CASRN 61702-44-1)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Negative 
      • Male Mice Negative 
      • Female Mice Negative 
    • Dose: R: 0, .15, .30, M: 0, .3, .6 %DIET/50 PER GROUP.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (110183)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Mouse Lymphoma  (962361)  Completed 
    • Mice
    •  Positive 
  • Salmonella  (832540)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Positive