Testing Status of Parathion 10942-W
CASRN: 56-38-2
Formula: C10-H14-N-O5-P-S
Synonyms/Common Names
- Phosphorothioic acid, O,O-diethyl O-(4-nitrophenyl)ester (9CI)
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C00226)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- 13-Week (Dosed-Feed)
(C00226)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0, 5, 320, M: 0, 160, 1280 PPM/5 PER GROUP.
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C00226)
Completed
- TR-070 (NIH Number: 79-1320)
(Peer Review Approval 08/31/1978A )
Bioassay of Parathion for Possible Carcinogenicity (CASRN 56-38-2) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Equivocal
- Female Rats Equivocal
- Male Mice Negative
- Female Mice Negative
- Dose: MR: 0, 32, 63 (AVG), FR: 0, 23, 45 (AVG), M: 0, 80, 160 PPM/50 PER GROUP.
- TR-070 (NIH Number: 79-1320)
(Peer Review Approval 08/31/1978A )
Special Studies
- C. elegans
(S0904)
Completed
- C. elegans
- Dose: repro: (0, .0025, .004, .0063, .01, .016, .025, .04, .063, .1, .16, .25) mM 08/30/06 GROWTH: (0, .01, .016, .025, .04, .063, .1, .16, .25, .40, .63, 1) mM 07/30/07Feed: (0, .0025, .004, .0063, .01, .016, .025, .04, .063, .1, .16, .25) mM 04/20/07.
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(580599)
Completed
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Negative
- Salmonella
(512404)
Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Weakly Positive
- Salmonella
(533981)
Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Negative