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Testing Status of Tetradecanoyl phorbol acetate (TPA) 11243-Y

 

CASRN: 16561-29-8

Formula: C36-H56-O8

Synonyms/Common Names

  • Phorbol myristate acetate
  • Tetradecanoic acid, 9a-(Acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b,dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa(3-,4)benz(1,2-E)azulen-9-yl

Short-Term Toxicity

  • 39 weeks (Topical Application)  (C96003D)  Completed 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: TG.AC: DERMAL TPA 1.25 UG/ANIMAL/DOSE.