Testing Status of Phenobarbital 11566-S
CASRN: 50-06-6
Formula: C12-H12-N2-O3
Synonyms/Common Names
- Phenobarbituric acid
Short-Term Toxicity
- GD 6 to PND 21 (Gavage)
(C11566)
Completed
- In Utero-PND 22 Exposure to Phenobarbital
- Rats: Wistar Han
- Dose: 0, 5, or 45 mg/kg; 10/group.
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(539978)
Completed
- Citation: Gulati, D., Sabharwal, P., and Shelby, M. Tests for the induction of chromosomal aberrations and sister chromatid exchanges in cultured Chinese hamster ovary (CHO) cells. In Evaluation of Short-Term Tests for Carcinogens, Elsevier/North Holland 413-426
- Sister Chromatid Exchange Negative
- Chromosome Aberrations Positive
- Mouse Lymphoma
(952103)
Completed
- Citation: Myhr, B., Bower, L., and Caspary, W. Assays for the induction of gene mutations at the thymine kinase locus in L1578Y mouse lymphoma cells in culture. In Evaluation of Short-Term Tests for Carcinogens, Elsevier/North Holland Vol. (1985) 555-568
- Mice
- Positive
- Salmonella
(338241)
Completed
- Citation: Zeiger, E., and Haworth, S. Tests with a preincubation modification of the Salmonella/microsome assay. In Evaluation of Short-Term Tests for Carcinogens Elsevier/North Holland 187-199
- Weakly Positive
Toxicogenomics
- Microarray Analysis (Gavage)
(T11566)
Completed
- In Utero - PND 22 Exposure to Phenobarbital
- Rats: Wistar Han